Home-Based Osteoporosis monitoring Using Bioelectrical Impedance Analysis: Muscle-to-Bone Mass Ratio

Author:

Zeng JingqiORCID,Jia Xiaobin

Abstract

AbstractOsteoporosis and its associated fractures affect nearly one-fifth of the global population, becoming a significant public health concern. While medical interventions can reduce these risks, Dual-energy X-ray Absorptiometry (DXA), the primary screening method, is limited due to its high cost, need for professional operation, and radiation exposure risks. However, in our Bioelectrical Impedance Analysis (BIA) conducted on 152,449 Chinese residents, we identified two distinct Muscle-to-Bone Mass Ratio (MBR) subgroups in both male and female elderly populations. The MBR range for males is 12.5-15.5 and 16.5-17.8; for females, it’s 11.2-15.2 and 16.5-18.2, with 16 being a significant threshold. Individuals with an MBR value exceeding 16 exhibit pronounced features of osteoporosis and an increased risk of fractures. For instance, the Bone Mineral Content (BMC) in males decreased by 19.18% (95%CI, 18.65%-19.73%), and in females by 29.84% (95%CI, 29.31%-30.36%). These individuals also showed lower body weight and BMI values. Females also displayed shorter stature and a higher body fat percentage, both indicators associated with osteoporosis. In contrast to the traditional Bone Mineral Density (BMD) T-score, the MBR sheds light on a specific physiological state in the elderly. In this condition, their risk of fractures significantly increases. This new understanding of osteoporosis suggests that we should not solely rely on the simple quantification of BMD. Furthermore, BIA measurements taken with domestic scales make MBR a safer, more efficient, and economical screening tool. This enables long-term MBR monitoring at home, offering continuous feedback for osteoporosis and fracture prevention, surpassing the limitations of DXA technology.

Publisher

Cold Spring Harbor Laboratory

Reference32 articles.

同舟云学术

1.学者识别学者识别

2.学术分析学术分析

3.人才评估人才评估

"同舟云学术"是以全球学者为主线,采集、加工和组织学术论文而形成的新型学术文献查询和分析系统,可以对全球学者进行文献检索和人才价值评估。用户可以通过关注某些学科领域的顶尖人物而持续追踪该领域的学科进展和研究前沿。经过近期的数据扩容,当前同舟云学术共收录了国内外主流学术期刊6万余种,收集的期刊论文及会议论文总量共计约1.5亿篇,并以每天添加12000余篇中外论文的速度递增。我们也可以为用户提供个性化、定制化的学者数据。欢迎来电咨询!咨询电话:010-8811{复制后删除}0370

www.globalauthorid.com

TOP

Copyright © 2019-2024 北京同舟云网络信息技术有限公司
京公网安备11010802033243号  京ICP备18003416号-3