Spontaneous network transitions predict somatosensory perception

Abstract

SummarySensory perception is essential for transforming incoming information in the brain into targeted behavior. Thus, variations in our perceptions are ubiquitously associated with human behavioral performance. Since our brains are everlastingly active, the question arises whether spontaneous brain activity relates to perceptual variability and subsequent task performance. We analyzed spontaneous whole-brain activity preceding the trials of an ambiguous tactile temporal discrimination task and identified time-resolved brain networks from the seconds before each trial. Transitions to a frontal and a multi-frequency network across the brain were essential for the correct percept. Conversely, incorrect percepts are mainly preceded by transitions to an alpha-parietal network. Moreover, brain switches occur faster during the period before stimulus presentation for correct stimuli detection, suggesting the need for enhanced network flexibility during this phase. Thus, the interaction between whole-brain networks in the spontaneous pre-stimulus period contributes to the perception during the task.