Investigating the Causal Role of Motor Brain Areas in Rhythm Reproduction: A Transcranial Direct Current Stimulation Study

Abstract

AbstractHumans have an intrinsic tendency to move to music. However, our understanding of the neural mechanisms underlying the music-movement connection remains limited, and most studies have used correlational methods. Here, we used transcranial direct current stimulation (tDCS) to investigate the causal role of four brain regions commonly involved in movement timing and beat perception: the supplementary motor area (SMA), left and right premotor cortices (PMC), and the right cerebellum. On three different days, subjects received anodal, cathodal, or sham stimulation while reproducing strong-beat, weak-beat, and non-beat rhythms via finger tapping. Each subject only received stimulation in one of the four brain regions. As the SMA appears to play a primary role in beat perception, while the premotor cortex and cerebellum appear to have a more general role in timing, we predicted that the SMA stimulation would affect reproduction of rhythms with a beat, whereas premotor and cerebellar stimulation would affect reproduction of sequences with no beat. As expected, reproduction accuracy depended on beat strength; strong-beat rhythms were more accurately reproduced than weak and non-beat rhythms. Unexpectedly, tDCS had no effect on reproduction accuracy in any brain region. Thus, we found no evidence that modulating brain excitability in SMA, PMC, or cerebellum altered accuracy of rhythm reproduction. We discuss the implications of these results and future perspectives for this research.