Multi-attribute decision-making in macaques relies on direct attribute comparisons

Abstract

AbstractIn value-based decisions, there are frequently multiple attributes, such as cost, quality, or quantity, that contribute to the overall goodness of an option. Since one option may not be better in all attributes at once, the decision process should include a means of weighing relevant attributes. Most decision-making models solve this problem by computing an integrated value, or utility, for each option from a weighted combination of attributes. However, behavioral anomalies in decision-making, such as context effects, indicate that other attribute-specific computations might be taking place. Here, we tested whether rhesus macaques show evidence of attribute-specific processing in a value-based decision-making task. Monkeys made a series of decisions involving choice options comprising a sweetness and probability attribute. Each attribute was represented by a separate bar with one of two mappings between bar size and the magnitude of the attribute (i.e., bigger=better or bigger=worse). We found that translating across different mappings produced selective impairments in decision-making. When like attributes differed, monkeys were prevented from easily making direct attribute comparisons, and choices were less accurate and preferences were more variable. This was not the case when mappings of unalike attributes within the same option were different. Likewise, gaze patterns favored transitions between like attributes over transitions between unalike attributes of the same option, so that like attributes were sampled sequentially to support within-attribute comparisons. Together, these data demonstrate that value-based decisions rely, at least in part, on directly comparing like attributes of multi-attribute options.Significance StatementValue-based decision-making is a cognitive function impacted by a number of clinical conditions, including substance use disorder and mood disorders. Understanding the neural mechanisms, including online processing steps involved in decision formation, will provide critical insights into decision-making deficits characteristic of human psychiatric disorders. Using rhesus monkeys as a model species capable of complex decision-making, this study shows that decisions involve a process of comparing like features, or attributes, of multi-attribute options. This is contrary to popular models of decision-making in which attributes are first combined into an overall value, or utility, to make a choice. Therefore, these results serve as an important foundation for establishing a more complete understanding of the neural mechanisms involved in forming complex decisions.