Author:
Franko R.,Franko Y.,Martinez E. Ribes,Ferronato G.A.,Heinzelmann I.,Grechi N.,Devkota S.,Fontes P.K.,Coeti R.,Oshiro T.S.I.,Ferraz M.A.M.M.
Abstract
AbstractUnderstanding the mechanical properties and porosity of reproductive tissues is vital for regenerative medicine in tissue engineering. This study investigated the changes in Young’s modulus (YM), storage modulus (E′), loss modulus (E″), and porosity of native and decellularized bovine reproductive tissues during the estrous cycle. Testis tunica albuginea had significantly higher YM, E′, and E″ than the inner testis, indicating greater stiffness and viscoelasticity. Endometrium showed no distinct differences in YM, E′, or E′ across the estrous cycle or between horns. Ovaries exhibited significant variations in YM, E′, E″, and porosity, with higher YM and E′ in the ipsilateral cortex and medulla during the luteal phase. Decellularized ovarian tissues displayed increased porosity. The oviduct displayed no significant differences in YM or E′ in the isthmus, but the contralateral ampulla had reduced YM and E′ in the luteal phase. These findings offer valuable insights into the dynamic mechanical properties and porosity of reproductive tissues, facilitating the development of biomimetic scaffolds for tissue engineering applications.
Publisher
Cold Spring Harbor Laboratory
Cited by
1 articles.
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