Author:
Larson Nicholas R.,Bou-Assaf George M.,Laue Thomas M.,Berkowitz Steven A.
Abstract
AbstractData are presented demonstrating that absorbance detection can be used during high-speed sedimentation velocity analytical ultracentrifugation (hs-SV-AUC) experiments to accurately characterize adeno-associated virus (AAV) drug products. Advantages and limitations of being able to use this detector in this specific type of SV-AUC experiment are discussed.
Publisher
Cold Spring Harbor Laboratory