Author:
Bhatt Gaurav,Rangan Latha,Limaye Anil Mukund
Abstract
AbstractKaranjin is an abundant furanoflavonoid-constitutent of pongamia oil. Among several biological actions of karanjin, the antiproliferative effect of karanjin has gained traction in the recent years; raising speculations about its anticancer potential. In the backdrop of partial estrogen-like alteration of gene expression by karanjin in ERα positive MCF-7 breast cancer cells, we present preliminary evidences supporting of the role of ERα in karanjin-mediated effects.
Publisher
Cold Spring Harbor Laboratory