Abstract
AbstractObjectivesTo quantify the association of social capital, defined as social relationships and networks, with cognitive health, oral inflammation, and epigenetic aging.MethodsWe used data from the Canadian Longitudinal Study on Aging (CLSA) (n=1,479; ages 45-85 years), categorizing social capital as structural and cognitive capital. Oral inflammation was determined as the presence of gum bleeding. Epigenetic aging was computed as the difference between chronological age and DNA methylation age. Multivariable regression models adjusted for covariates were used.ResultsHigher structural social capital was associated with decelerated epigenetic aging and better cognitive health outcomes. Higher cognitive social capital was also associated with better cognitive outcomes and less oral inflammation.ConclusionEnhancing social capital may contribute to better clinical and biological outcomes around aging.Visual Abstract
Publisher
Cold Spring Harbor Laboratory
Reference49 articles.
1. Cognitive impairment in COPD: should cognitive evaluation be part of respiratory assessment?;Breathe (Sheffield, England),2017
2. Biological embedding of experience: A primer on epigenetics
3. Victoria Stroop Test: Normative Data in a Sample Group of Older People and the Study of Their Clinical Applications in the Assessment of Inhibition in Alzheimer's Disease
4. Bourdieu P. (1986). The forms of capital. In Handbook of Theory and Research for the Sociology of Education. (pp. 241–258). https://www.socialcapitalgateway.org/content/paper/bourdieu-p-1986-forms-capital-richardson-j-handbook-theory-and-research-sociology-educ
5. Campagnol, P. B ., do Amaral Júnior, O. L. , Fagundes, M. L. B. , Menegazzo, G. R. , Neves, M. , Maroneze, M. C. , & do Amaral Giordani, J. M . (2022). Social capital and dental service use in older Brazilians. Gerodontology. https://doi.org/10.1111/GER.12658