Whole-Genome Sequence of African Swine Fever Virus isolate from India provides insights into diversity and evolution

Author:

Mahajan SonalikaORCID,Doley Juwar,Subramaniam Saravanan,Yadav Ajay K.,Pegu Seema Rani,Mohan Narayana H.,Chander Vishal,Mathesh Karikalan,Nandi Sukdeb,Singh Karam Pal,Gupta Vivek Kumar,Sharma Gaurav Kumar

Abstract

AbstractAfrican swine fever (ASF) was first reported in 1921, and since then has posed a major threat to the world pig industry and still remains a major challenge as there is no vaccine or therapy available. In May 2020, the first incidence of ASF was recorded in India, followed by a number of outbreaks in the north eastern part of India. In this study, we report the first whole genome of an Indian isolate of ASF virus (ASF/IND/20/CAD/543) using next generation sequencing and compared with the other ASFV complete genome. On phylogenetic analysis, the virus was assigned to genotype II on the basis of p72 genotyping. However, the whole genome based phylogeny distinguished it from other genotype II isolates of clade 1.1.1. This study adds to our understanding of ASFV’s genetic diversity and molecular evolution.

Publisher

Cold Spring Harbor Laboratory

Cited by 1 articles. 订阅此论文施引文献 订阅此论文施引文献,注册后可以免费订阅5篇论文的施引文献,订阅后可以查看论文全部施引文献

1. Tackling African swine fever in India;CABI Reviews;2023-12-22

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