DelaySSAToolkit.jl: stochastic simulation of reaction systems with time delays in Julia

Author:

Fu Xiaoming,Zhou Xinyi,Gu Dongyang,Cao Zhixing,Grima RamonORCID

Abstract

AbstractSummaryDelaySSAToolkit.jl is a Julia package for modelling reaction systems with non-Markovian dynamics, specifically those with time delays. These delays implicitly capture multiple intermediate reaction steps and hence serve as an effective model reduction technique for complex systems in biology, chemistry, ecology and genetics. The package implements a variety of exact formulations of the delay stochastic simulation algorithm.Contactxmfu@ecust.edu.cn, zcao@ecust.edu.cn, or ramon.grima@ed.ac.ukAvailability and ImplementationThe source code and documentation of DelaySSAToolkit.jl are available at https://github.com/palmtree2013/DelaySSAToolkit.jl.

Publisher

Cold Spring Harbor Laboratory

Reference21 articles.

1. A modified next reaction method for simulating chemical systems with time dependent propensities and delays;Journal of Chemical Physics,2007

2. On the interpretation of delays in delay stochastic simulation of biological systems;Electronic Proceedings in Theoretical Computer Science, EPTCS,2009

3. Oscillatory regulation of hes1: Discrete stochastic delay modelling and simulation;PLoS Computational Biology,2006

4. Delay-induced stochastic oscillations in gene regulation

5. Exact stochastic simulation of coupled chemical reactions with delays;Journal of Chemical Physics,2007

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