3D-Printable Non-invasive Head Immobilization System for Non-Human Primates

Abstract

AbstractWe introduce a novel 3D-printed non-invasive head immobilization system (NHIS) for macaque monkeys, addressing the limitations of traditional head fixation methods in behavioral experiments. Traditional techniques, crucial for precise eye movement tracking and neural recording, often lead to biological complications like infection and bone softening. Our innovative NHIS, designed using CT/MRI scans and custom software FLoRIN, offers a tailored, comfortable fit for each subject. It accommodates essential experimental equipment such as eye-tracking and physiological monitoring devices, providing a more adaptable and efficient alternative for nonhuman primate research. Our results demonstrate that the NHIS significantly reduces the risk of infection and bone damage while maintaining high precision in eye-tracking data, making it a superior choice for long-term studies.