Abstract
While there is substantial evidence that the dorsal and ventral hippocampus play different roles during emotional learning, it is unknown how these roles are implemented. Here, we simultaneously recorded in these structures during fear conditioning, and demonstrated a predominance of responses related to fear expression in dorsal hippocampus, while ventral hippocampal responses were more closely linked with the acquisition of conditioned fear. Furthermore, cell assemblies containing both dorsal and ventral neurons emerged during fear conditioning, therefore suggesting a potential substrate to integrate these complementary signals for learning and behavior.
Publisher
Cold Spring Harbor Laboratory