Possible roles of phytochemicals with bioactive properties in the prevention of and recovery from COVID-19

Author:

Koyama SachikoORCID,Shields Vonnie D.C.ORCID,Heinbockel ThomasORCID,Joseph Paule V.ORCID,Adhikari Poonam,Kaur RishemjitORCID,Kumar RiteshORCID,Alizadeh RafiehORCID,Bhutani Surabhi,Calcinoni OriettaORCID,Mucignat-Caretta CarlaORCID,Chen JingguoORCID,Cooper Keiland W.ORCID,Das Subha R.ORCID,Domínguez Paloma RohlfsORCID,Guàrdia Maria DolorsORCID,Klyuchnikova Maria A.ORCID,Laktionova Tatiana K.ORCID,Mori EriORCID,Namjoo ZeinabORCID,Nguyen HaORCID,Özdener Mehmet HakanORCID,Parsa ShimaORCID,Poyraz Elif ÖzdenerORCID,Strub Daniel JanORCID,Taghizadeh-Hesary FarzadORCID,Ueha RumiORCID,Voznessenskaya Vera V.ORCID

Abstract

AbstractPurposeThere have been large geographical differences in the infection and death rates of COVID-19. Foods and beverages containing high amounts of phytochemicals with bioactive properties were suggested to prevent contracting, to limit the severity of, and to facilitate recovery from COVID-19. The goal of our study was to determine the correlation of the type of foods/beverages people consumed and the risk reduction of contracting COVID-19 and the recovery from COVID-19.MethodsWe developed an online survey that asked the participants whether they contracted COVID-19, their symptoms, time to recover, and their frequency of eating various types of foods/beverages. The survey was first developed in English and then translated into 10 different languages.ResultsThe participants who did not contract COVID-19 consumed vegetables, herbs/spices, and fermented foods/beverages significantly more than the participants who contracted COVID-19 and those who were not tested but became sick most likely from COVID-19. The geographic location of participants corresponded with the language of the survey, except for the English version, thus, nine out of the 10 language versions represented a country. Among the six countries (India, Iran, Italy, Japan, Russia, Spain) with over one hundred participants, we found that in India and Japan the people who contracted COVID-19 showed significantly shorter recovery time, and greater daily intake of vegetables, herbs/spices, and fermented foods/beverages was associated with faster recovery.ConclusionOur results suggest that phytochemical compounds included in the vegetables may have contributed in not only preventing contraction of COVID-19, but also accelerating their recovery. (249 words; EJN limit is 250 words)

Publisher

Cold Spring Harbor Laboratory

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