Abstract
ABSTRACTDatabases of genes and enzymes involved in natural and synthetic hydrocarbon degradation have been previously reported. However, these databases specialize on only a specific group of hydrocarbons and/or are constructed partly based on enzyme sequences with putative functions indicated by in silico research, with no experimental evidence. Here, we present a curated database of Hydrocarbon Aerobic Degradation Enzymes and Genes (HADEG) containing enzymes and genes involved in alkane, alkene, aromatic, and polymer aerobic degradation and biosurfactant production based solely on experimental evidence. HADEG includes 259 enzymes for petroleum hydrocarbon degradation, 160 for polymer degradation, and 32 for biosurfactant production. This database will help identify and predict hydrocarbon degradation genes/pathways and biosurfactant production in genomes.
Publisher
Cold Spring Harbor Laboratory