Author:
Gentry Katherine A.,Anantharamaiah G. M.,Ramamoorthy Ayyalusamy
Abstract
AbstractCytochrome P450 (cytP450) interacts with two redox partners, cytP450 reductase and cytochrome-b5, to metabolize substrates. Using NMR, we reveal changes in the dynamic interplay when all three proteins are incorporated into lipids nanodiscs in the absence and presence of substrates.
Publisher
Cold Spring Harbor Laboratory