Single-molecule long-read methylation profiling reveals regional DNA methylation regulated by Elongator Complex Subunit 2 inArabidopsisroots experiencing spaceflight

Author:

Zhou MingqiORCID,Riva Alberto,Gauthier Marie-Pierre L.,Kladde Michael P.ORCID,Ferl Robert J.ORCID,Paul Anna-LisaORCID

Abstract

AbstractFlap-Enabled Next-Generation Capture (FENGC), a novel targeted DNA capture technique, has been applied to Arabidopsis root samples from the Advanced Plant Experiment-04 - Epigenetic Expression (APEX-04) experiment onboard the International Space Station (ISS). Single-molecule long-read profiling reveals regional DNA methylation alteration that was not previously uncovered by population-based methods during spaceflight.

Publisher

Cold Spring Harbor Laboratory

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