Geneplot: a coordinate conversion approach for graphical representation of protein domain data on the exon-intron structure of a gene

Abstract

AbstractGraphical representation of single gene data, including subgenic features, polymorphisms and protein domains, is part of the regular routine of genome analyses. In the case of protein-coding genes, integration of such information with the exon-intron structure has advantages since intron polymorphisms may also have a biological impact, and the extent to which exons and protein domains overlap is of interest to evolutionary research. This report introducesgeneplot, an open-source Python library to generate this type of graphical output from standard file formats. The library applies a coordinate conversion approach in order to represent protein domain data on genomic areas.