Modulation of beta oscillatory dynamics in motor and frontal areas during physical fatigue

Abstract

AbstractBeta-band oscillations have been suggested to promote the maintenance of the current motor (or cognitive) set, thus signaling the ‘status quo’ of the system. While this hypothesis has been reliably demonstrated in many studies, it fails to explain changes in beta-band activity due to the accumulation of physical fatigue. In the current study, we aimed to reconcile the functional role of beta oscillations during physical fatigue within the status quo theory. Using an innovative EEG design, we identified two distinct beta-band power dynamics in the motor areas as fatigue rises: (i) an enhancement at rest, supposedly promoting the resting state, and (ii) a decrease during contraction, thought to reflect the increase in motor cortex activation necessary to cope with the muscular fatigue. We then conducted effective connectivity analyses, which revealed that the modulations during contractions were driven by frontal areas. Finally, we implement a biologically plausible model to replicate and characterize our results mechanistically. Together, our findings anchor the physical fatigue paradigm within the status quo theory, thus shedding light on the functional role of beta oscillations in physical fatigue. We further discuss a unified interpretation that might explain the conflicting evidence previously encountered in the physical fatigue literature.