Risk Factors of Multi-Drug Resistant Tuberculosis among Tuberculosis Patients in Province 3, Nepal: A case-control study-Reference-Cited by-同舟云学术

Risk Factors of Multi-Drug Resistant Tuberculosis among Tuberculosis Patients in Province 3, Nepal: A case-control study

Published:2024-06-18 Issue: Volume: Page:
ISSN:
Container-title:
language:
Short-container-title:

Author:

Acharya Puspa^ORCID,Bhattarai Niraj,Kunwar Bhuban Raj,Sharma Khem Raj,Khanal Vijay Kumar^ORCID,Yadav Birendra Kumar

Abstract

AbstractBackgroundDrug-resistant tuberculosis poses a significant threat to global TB control efforts, potentially reversing progress made in reducing TB-related morbidity and mortality. This study aims to identify risk factors for multidrug-resistant TB [MDR-TB] in Province 3, Nepal.MethodologyA case-control study was conducted by matching TB-infected patients undergoing MDR-TB treatment and DS-TB treatment by gender. Data was collected through structured questionnaires and interviews and analyzed using binary logistic regression.ResultsSignificant risk factors for MDR-TB included Pulmonary Tuberculosis [PTB], previous TB treatment history, close contact with DR-TB patients, and subjective feelings of sadness.ConclusionThe study highlights the importance of prevention measures to break transmission chains and infection control in health facilities. Additionally, it underscores the need for mental health support for TB patients.

Publisher

Cold Spring Harbor Laboratory

Reference52 articles.

1. WHO. Global tuberculosis report 2019. Geneva: World Health Organization; 2019. Licence: CC BY-NC-SA 3.0 IGO. 2019.

2. Tuberculosis: a global emergency;Work,1997

3. World Health Organization. What is DOTS ? A Guide to Understanding the WHO-recommended TB Control Strategy Known as DOTS. Prev Control [Internet]. 1999;1–39. Available from: https://apps.who.int/iris/handle/10665/65979

4. Building a tuberculosis-free world: The Lancet Commission on tuberculosis;Lancet [Internet,2019

5. WHO. Follow-up to the high-level meetings of the UN General Assembly on health-related issues AMR Report by the Director-General. Seventy-second World Heal Assem [Internet]. 2019;(April):1–11. Available from: https://amrcountryprogress.org.