Abstract
AbstractDaphnia, an emerging model system for the study of evolution, development, phenotypic plasticity, and environmental health, lacks a modern reference atlas for microanatomy. To facilitate the recognition of phenotype caused by the change in genes and environment in theDaphnia, we have created theDaphniaHistologyReferenceAtlas (DaHRA,http://daphnia.io/anatomy/). The atlas presents histology of female and maleDaphniain three anatomical planes. This interactive web-based resource features overlaid, vectorized annotations that are compliant with an anatomical ontology created for this atlas. We demonstrate the use of DaHRA to contextualize sexual dimorphism inDaphnia, and its potential application to the study of tissue toxicity. The web-based documentation of tissue structure can potentially be used in support of unbiased, whole-organism phenotyping in the study of biology and disease.
Publisher
Cold Spring Harbor Laboratory