Mapping in the region of Danforth's short tail and the localization of tail length modifiers.-Reference-Cited by-同舟云学术

Mapping in the region of Danforth's short tail and the localization of tail length modifiers.

Published:1997-02 Issue:2 Volume:7 Page:108-117
ISSN:1088-9051
Container-title:Genome Research
language:en
Short-container-title:Genome Res.

Author:

Alfred J B,Rance K,Taylor B A,Phillips S J,Abbott C M,Jackson I J

Abstract

We have used an interspecific backcross to generate a detailed genetic map around the mouse tail and kidney developmental mutation Danforth's short tail (Sd). The map includes 14 simple sequence repeat (SSR) markers and four genes in a 5-cM region encompassing Sd. In addition we have used a DNA pooling approach to carry out a genome scan to localize quantitative trait loci (QTL) that modify the tail length of Sd progeny of the backcross. This has allowed us to identify a major QTL on chromosome 10 in the region of nodal and three other putative tail length QTL on chromosomes 1, 9, and 18.

Publisher

Cold Spring Harbor Laboratory

Subject

Genetics(clinical),Genetics

Reference29 articles.

1. Transformation of axial skeleton due to overexpression of bmi-1 in transgenic mice

2. Chromosome 2: Distance of Sd from centromere.;Mouse News Lett.,1980

3. A primary requirement for nodal in the formation and maintenance of the primitive streak in the mouse.;Development,1994

4. Selective DNA pooling for determination of linkage between a molecular marker and a quantitative trait locus.;Genetics,1994

5. Altered Pax gene expression in murine notochord mutants: the notochord is required to initiate and maintain ventral identity in the somite

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