Mapping in the region of Danforth's short tail and the localization of tail length modifiers.-Reference-Cited by-同舟云学术

Mapping in the region of Danforth's short tail and the localization of tail length modifiers.

Published:1997-02 Issue:2 Volume:7 Page:108-117
ISSN:1088-9051
Container-title:Genome Research
language:en
Short-container-title:Genome Res.

Author:

Alfred J B,Rance K,Taylor B A,Phillips S J,Abbott C M,Jackson I J

Abstract

We have used an interspecific backcross to generate a detailed genetic map around the mouse tail and kidney developmental mutation Danforth's short tail (Sd). The map includes 14 simple sequence repeat (SSR) markers and four genes in a 5-cM region encompassing Sd. In addition we have used a DNA pooling approach to carry out a genome scan to localize quantitative trait loci (QTL) that modify the tail length of Sd progeny of the backcross. This has allowed us to identify a major QTL on chromosome 10 in the region of nodal and three other putative tail length QTL on chromosomes 1, 9, and 18.

Publisher

Cold Spring Harbor Laboratory

Subject

Genetics(clinical),Genetics

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