FERROKINETIC EVALUATION OF PATIENTS WITH ACUTE CORONARY SYNDROME AT A SOUTH AMERICAN HOSPITAL, PILOT STUDY

Author:

Dulcey Sarmiento Luis AndresORCID,Theran Leon Juan SebastiánORCID,Peña Valentina CabreraORCID,Parales Strauch Rafael GuillermoORCID,Caltagirone RaimondoORCID,Blanco Pimiento Edgar CamiloORCID,Ciliberti Artavia María PaulaORCID,Martinez Juan CamiloORCID

Abstract

AbstractIntroductionAlterations in the ferrokinetic profile are associated with cardiovascular disease, and the short- and long-term prognosis of these alterations is currently unknown.DesignProspective cohort analytical observational studyMethodsTo determine the prognostic value of the alterations of the ferrokinetic profile in patients with myocardial infarction with and without ST-segment elevation, in a Health institution from July 2017 to May 2018. Results : From72patients, the main affected gender was male, in ages over 56 years old, the infarction with ST elevation being the most frequent. Among the associated comorbidities, the main one was hypertension with (n: 22; 53.7%) for infarction with elevation and (n: 23; 74.2%) for infarction without ST elevation. The most frequent alteration of the parameters of the ferrokinetic profile studied, was the iron deficit, found in (n:15; 36.6%) of the patients with ST elevation and (n:13; 41.9%) without ST elevation. Low levels of hemoglobin were present at admission (n:10; 24.4%) of the subgroup with ST elevation and (n:10; 32.3%) for no ST elevation, increasing the percentage to (n:13; 31.7%) (RR: 2) (95% CI -0.131-30.63), associated with low hemoglobin values at day 7 of hospitalization. There were 2 deaths (2.77%), which presented low levels of iron without anemia and infarction with ST elevation complicated by cardiogenic shock.Conclusionsiron deficiency is a common comorbidity with a high mortality rate, and the decrease in hemoglobin after hospital admission was related to mortality, so both parameters should be taken into account in Infarction and cardiovascular disease.

Publisher

Cold Spring Harbor Laboratory

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