Prevalence of anemia, associated risk factors and outcome in CHUK, Rwanda: a prospective observational study

Abstract

ABSTRACTBackgroundAdmitted patients with anemia are at increased morbidity and mortality risk as well as length of hospital stay. It affects more than 2 billion people worldwide and is causing significant morbidity and mortality. Its etiology is varying with many predisposing factors including nutritional deficiencies, infections, Malignancies, chronic inflammations and other chronic diseases like autoimmune diseases, chronic liver disease, and chronic kidney disease.MethodsWe performed a non-randomized, prospective observational study of 143 patients admitted in Internal Medicine between March and April 2021, we assessed their hemoglobin level in order to determine the prevalence of anemia. The demographic and clinical data were collected using a designed questionnaire. All patients found to have anemia were followed for outcome assessment (either discharge or died).ResultsThe prevalence of anemia was high (52.4%) among 143 admitted patients in Internal Medicine, CHUK. Patients with HIV, cancer and chronic kidney disease had 5.84-, 4.11- and 3.79-times risk of having anemia respectively. In 75 patients who had anemia 10 patients died among them 5 patients were having severe anemia; 25 patients were 60 years old and above; 60 patients had normocytic anemia and they had an average of length of hospital stay of 20.6 days, patients with severe anemia, length of hospital stay was 28 days.ConclusionThis study demonstrated a high prevalence of anemia which is associated with high mortality rate among admitted patients in CHUK. Priority should be given to the preventive medicine, optimal management of chronic disease and geriatric medicine.