Sedentary time in adults with cystic fibrosis: A prospective observational cross-sectional study

Abstract

AbstractObjectiveAdults with cystic fibrosis remain susceptible to comorbidities associated with high sedentary time, increasing their risk of poor health outcomes. Evidence about sedentary time in adults with cystic fibrosis is limited. This study investigated sedentary time and physical activity in adults with cystic fibrosis across disease severity groups and the relationship with clinical measures.MethodsA SenseWear armband was worn by adults with cystic fibrosis, measuring sedentary time, time spent in moderate-vigorous physical activity and steps per day. Lung function, quadriceps strength, exercise capacity and health-related quality of life were assessed.ResultsOn average, the armband was worn for 20 hours (Standard Deviation (SD) 6) over 6 (SD 1) days. Forty-eight participants (28 males) spent 815 (SD 379) minutes sedentary, 137 (SD 13) minutes engaged in moderate-vigorous physical activity and took 5660 (SD 2749) steps per day. Sedentary time did not vary across disease severity groups nor correlate with clinical measures.ConclusionsAdults with cystic fibrosis spent a large proportion of time in sedentary behaviours, took insufficient steps, but conversely engaged in sufficient moderate-vigorous physical activity. Targeted interventions to break up sedentary time are required to reduce the risk of adverse health outcomes in this population.ImpactAdults with cystic fibrosis spend a large proportion of their time sedentary, placing them at risk of future metabolic disorders. Interventions to break up sedentary time are needed.