Next weeks of SARS-CoV-2: Projection model to predict time evolution scenarios of accumulated cases in Spain

Author:

Monleon-Getino AntonioORCID,Canela-Soler JaumeORCID

Abstract

AbstractBackground and objectivesSARS-CoV-2 is a new type of coronavirus that can affect people and causes respiratory disease, COVID-19. It is affecting the entire planet and we focus in Spain, where the first case was detected at the end of January 2020 and in recent weeks it has increased in many cases. We need predictive models in order to be efficient and take actions. The general goal of this work is present a new model of SARS-CoV-2 to predict different scenarios of accumulated cases in Spain.Material and methodsIn this short report is used a model proposed previously, based on a parametric model Weibull and in a the library BDSbiost3 developed in R to infer and predict different scenarios of the evolution of SARS-CoV-2 for the accumulated cases in Spain after the spread that affects Spain detected at the end of January of this year.ResultsIn the analyses presented, projective curves have been generated for the evolution of accumulated cases in which they reach about 4,000 cases or about 15,000 cases, for which the lines of the day in which the value for 90 will be reached can be seen vertically 90, 95 and 99% of the asymptote (maximum number of cases, from that day they will begin to descend or remain the same), that is why the vertical lines would indicate the brake of the disease. For the worst-case scenario, it takes 118, 126 or 142 days to reach the maximum number of cases (n = 15,000) to reach 90, 95 and 99% of the asymptote (maximum number of cases), respectively. This means translated in a time scale that in the worst case the virus will not stop its progress, in Spain, until summer 2020, hopefully before.Comments and conclusionsThis model could be used to plan the resources and see if the policies or means dedicated to the virus are slowing the progress of the virus or it is necessary to implement others that are more effective, and can also validate a method for future outbreaks of diseases such as these.

Publisher

Cold Spring Harbor Laboratory

Reference6 articles.

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2. Ministry of Health, Spain. 2020. Coronavirus data for Spain https://www.mscbs.gob.es/profesionales/saludPublica/ccayes/alertasActual/nCov-China/situacionActual.htm. EPDATA. Interactive maps of coronavirus for Spain https://www.epdata.es/datos/coronavirus-china-datos-graficos/498

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4. Use of non-linear mixed-effects modelling and regression analysis to predict the number of somatic coliphages by plaque enumeration after 3 hours of incubation

5. Toni Monleon-Getino , Jorge Frias-Lopez . 2020. A priori estimation of sequencing effort in complex microbial metatranscriptomes (Pending of publication, Methods in Ecology, sent 2020)

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