Abstract
SummaryThe Betta fish displays a remarkable variety of phenotypes selected during domestication. However, the genetic basis underlying these traits remain largely unexplored. Here, we report a high-quality genome assembly and re-sequencing of 727 individuals representing diverse morphologies of the betta fish. We show that current breeds have a complex domestication history with extensive introgression with wild species. Using GWAS, we identify the genetic basis of multiple traits, including several coloration phenotypes, sex-determination which we map to DMRT1, and the long-fin phenotype which maps to KCNJ15. We identify a polygenic signal related to aggression with many similarities to human psychiatric traits, involving genes such as CACNB2 and DISC1. Our study provides a resource for developing the Betta fish as a genetic model for morphology and behavior in vertebrates.
Publisher
Cold Spring Harbor Laboratory
Reference48 articles.
1. W. J. Rainboth , FISHES OF THE CAMBODIAN MEKONG (Food And Agriculture Organization Of The United Nations Press, Rome, 1996).
2. H. M. Smith , The Fresh-water fishes of Siam (Bulletin of the United States National MuseumPress, Washington, 1945).
3. Die Umwelt des Kampffisches (Betta Splendens Regan);Zeitschrift für vergleichende Physiologie,1932
4. Genetics and Colors of the Siamese Fighting Fish,
Betta splendens
5. Über die Vererbung der Farben und des Geschlechts beim Schleierkampffish Betta Splendens;Zeitschrift für Induktive Abstammungs & Vererbungslehre,1939
Cited by
8 articles.
订阅此论文施引文献
订阅此论文施引文献，注册后可以免费订阅5篇论文的施引文献，订阅后可以查看论文全部施引文献