Author:
Diaz Jairo A,Sánchez Liliana,Diaz Luis A,Murillo Mauricio F,Poveda Laura,Mora Katherine,Suescun Oscar F,Cardenas Monica,Castro Laura
Abstract
ABSTRACTEvery cancer cell can partially or completely return to an embryonic genotype-phenotype: We were able to capture the evolutionary cycle of the activation of an individual cellular memory, which allowed a group of squamous tumor cells with mutations caused by the Human Papilloma Virus to return collectively to an embryoid-like state, in unique images. Somatic cells have the plasticity to transform their morphology into an embryonic phenotype when they enter a state of cellular emergency.Our findings document how malignant tissues reactivated ancestral storage memory and elaborate, high-fidelity crystalline fractal chiral structures (Tc) repaired copies from damaged substrate tissue. Harnessing this resultant perfect embryoblast memory template probably guides and controls the regenerative pathway mechanism in human tissues as follows: a) Modify and reprogram the phenotype of the tumor where these entities are generated. b) Establish a reverse primordial microscopic mold to use the collective behavior of cellular building blocks to regenerate injured tissues. c) Convert cancer cells to a normal phenotype by developmental patterning of active patterning cues. d) Convert cancer cells to a normal phenotype by regeneration using the organizational level and scale properties of reverse genetic guidance. e) Globally control mitotic activity and morphogenetic movements, preventing its spread and metastasis, determining a better prognosis for patients who incubate these entities in their tumors compared to those who do not express them. f) Under physical-chemical cellular stress it is possible to artificially replicate these entities from the epithelium of minor salivary glands in humans.
Publisher
Cold Spring Harbor Laboratory