Outcomes of COVID-19: disparities by ethnicity
Author:
Ali HamadORCID, Alshukry Abdullah, Marafie Sulaiman K, AlRukhayes Monera, Ali Yaseen, Abbas Mohammad Bu, Al-Taweel Abdullah, Bukhamseen Yousef, Dashti Mohammad H, Al-Shammari Abdullah, Abu-Farha MohammadORCID, AbuBaker Jehad, Al-Mulla Fahd
Abstract
AbstractObjectivesTo investigate the role of ethnicity in COVID-19 outcome disparities in a cohort in Kuwait.MethodsThis is a retrospective analysis of 405 individuals infected with SARS-CoV-2 in Kuwait. Outcomes such as symptoms severity and mortality were considered. Multivariate logistic regression models were used to report the odds ratios (OR) for ICU admission and dying from COVID-19.ResultsThe cohort included 290 Arabs and 115 South Asians. South Asians recorded significantly higher COVID-19 death rates compared to Arabs (33% vs. 7.6%, P value<0.001). When compared to Arabs, South Asians also had higher odds of being admitted to the ICU (OR = 6.28, 95% CI: 3.34 – 11.80, p < 0.001). South Asian patients showed 7.62 (95% CI: 3.62 – 16.02, p < 0.001) times the odds of dying from COVID-19.ConclusionCOVID-19 patients with South Asians ethnicity are more likely to have worse prognosis and outcome when compared to patients with Arab ethnicity. This suggest a possible role for ethnicity in COVID-19 outcome disparities and this role is likely to be multifactorial.
Publisher
Cold Spring Harbor Laboratory
Reference5 articles.
1. Al-Mulla, F. , Mohammad, A. , Al Madhoun, A. , Haddad, D. , Ali, H. , Eaaswarkhanth, M. , John, S.E. , Nizam, R. , Channanath, A. , Abu-Farha, M. , Ahmad, R. , Abubaker, J. , Thanaraj, T.A. , 2020. A comprehensive germline variant and expression analyses of ACE2, TMPRSS2 and SARS-CoV-2 activator FURIN genes from the Middle East: Combating SARS-CoV-2 with precision medicine. bioRxiv, 2020.2005.2016.099176. 2. Ali, H. , Alshukry, A. , Bu Abbas, M. , Ali, Y. , Alahmad, B. , Al-Shammari, A.A. , Abu-farha, M. , Abubakr, J. , Devarajan, S. , Dashti, A.A. , Al-Mulla, F. , 2020. Clinical Characteristics and Outcomes of Diabetic COVID-19 patients in Kuwait. medRxiv, 2020.2008.2020.20178525. 3. Alshukry, A. , Ali, H. , Ali, Y. , Al-Taweel, T. , Abu-farha, M. , AbuBaker, J. , Devarajan, S. , Dashti, A.A. , Bandar, A. , Taleb, H. , Al Bader, A. , Aly, N.Y. , Al-Ozairi, E. , Al-Mulla, F. , Bu Abbas, M. , 2020. Clinical characteristics of Coronavirus Disease 2019 (COVID-19) patients in Kuwait. medRxiv, 2020.2006.2014.20131045. Central Statistical Bureau of Kuwait (CSBoK), 2019. Annual Statistical 2019. 4. Hospitalization Rates and Characteristics of Patients Hospitalized with Laboratory-Confirmed Coronavirus Disease 2019 — COVID-NET, 14 States, March 1–30, 2020 5. Ethnicity and covid-19
Cited by
1 articles.
订阅此论文施引文献
订阅此论文施引文献,注册后可以免费订阅5篇论文的施引文献,订阅后可以查看论文全部施引文献
|
|