Development of the PSYCHS: Positive SYmptoms and Diagnostic Criteria for the CAARMS Harmonized with the SIPS

Author:

Woods Scott W.,Parker Sophie,Kerr Melissa J.,Walsh Barbara C.,Wijtenburg S. Andrea,Prunier Nicholas,Nunez Angela R.,Buccilli Kate,Mourgues-Codern Catalina,Brummitt Kali,Kinney Kyle S.,Trankler Carli,Szacilo Julia,Colton Beau-Luke,Ali Munaza,Haidar Anastasia,Billah Tashrif,Huynh Kevin,Ahmed Uzair,Adery Laura L.,Corcoran Cheryl M.,Perkins Diana O.,Schiffman Jason,Perez Jesus,Mamah Daniel,Ellman Lauren M.,Powers Albert R.,Coleman Michael J.,Anticevic Alan,Fusar-Poli Paolo,Kane John M.,Kahn Rene S.,McGorry Patrick D.,Bearden Carrie E.,Shenton Martha E.,Nelson Barnaby,Calkins Monica E.,Hendricks Larry,Bouix Sylvain,Addington Jean,McGlashan Thomas H.,Yung Alison R.,Allott Kelly,Clark Scott R.,Kapur Tina,Lavoie S.,Lewandowski Kathryn E.,Mathalon Daniel H.,Pasternak Ofer,Stone William S.,Torous John,Rowland Laura M.,Zhan Ming,Amminger Paul,Arango Celso,Broome Matthew R.,Cadenhead Kristin S.,Chen Eric Y.H.,Choi Jimmy,Kevin Cho Kang Ik,Conus Philippe,Cornblatt Barbara A.,Glenthøj Louise Birkedal,Horton Leslie E.,Kambeitz Joseph,Keshavan Matcheri S.,Koutsouleris Nikolaos,Langbein Kerstin,Diaz-Caneja Covadonga Martinez,Mittal Vijay A.,Nordentoft Merete,Gaspar Ramos Pablo A.,Pearlson Godfrey D.,Shah Jai L.,Smesny Stefan,Strauss Gregory P.,Wang Jijun,Marcy Patricia J.,Matneja Priya,Phassouliotis Christina,Ray Susan,Snowball Collum,Spark Jessica,Tod Sophie, , , , , ,

Abstract

AbstractAimTo harmonize two ascertainment and severity rating instruments commonly used for the clinical high risk syndrome for psychosis (CHR-P): the Structured Interview for Psychosis-risk Syndromes (SIPS) and the Comprehensive Assessment of At-Risk Mental States (CAARMS).MethodsThe initial workshop is described in the companion report from Addington et al. After the workshop, lead experts for each instrument continued harmonizing attenuated positive symptoms and criteria for psychosis and CHR-P through an intensive series of joint videoconferences.ResultsFull harmonization was achieved for attenuated positive symptom ratings and psychosis criteria, and partial harmonization for CHR-P criteria. The semi-structured interview, namedPositiveSYmptoms and Diagnostic Criteria for theCAARMSHarmonized with theSIPS (PSYCHS), generates CHR-P criteria and severity scores for both CAARMS and SIPS.ConclusionUsing the PSYCHS for CHR-P ascertainment, conversion determination, and attenuated positive symptom severity rating will help in comparing findings across studies and in meta-analyses.

Publisher

Cold Spring Harbor Laboratory

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