The neural organization of visual information in the auditory cortex of the congenitally deaf

Abstract

SummaryNeuroplasticity is the ability of the human brain to reorganize and modify its activity throughout life. In congenital deafness, sensory-deprived cortex can be recruited to represent sensory information belonging to other modalities, a process known as cross-modal plasticity. Previous studies have indicated that the auditory cortex of congenitally deaf, but not of hearing individuals, is recruited during visual tasks. However, it is not clear to what extent, and how, these cross-modal responses in the deprived auditory cortex represent low-level visual spatial information or map the visual field. Here, we addressed this question directly in an fMRI case-study, aiming to map retinotopic features in the auditory cortex. Two congenitally deaf and one hearing participant went through a conventional retinotopy fMRI experiment with visual stimuli designed to map the visual system. Using population receptive field (pRF) modelling, we revealed retinotopic-related responses in the auditory cortex of the deaf, but not in the hearing. These responses, that were mostly lateralized to the right hemisphere, represented the contralateral visual field, and were characterized by large receptive fields, centred to near foveal areas. Interestingly, we found that these responses to visual stimuli predominantly reflected negative BOLD signals in the auditory cortex of the deaf, suggesting that visual information might be represented through cross-modal deactivation signals.