Author:
Vanramliana ,Pautu Lalfakzuala,Lalmalsawma Pachuau,Rosangkima Gabriel,Sarma Devojit Kumar,Hunropuia ,Malvi Yogesh,Kodali Naveen Kumar,Amarthaluri Christiana,Balasubramani K,Nina Praveen Balabaskaran
Abstract
AbstractIn the last decade, there has been an emergence of scrub typhus in many parts of India. In Mizoram, North-East India, there has been a steep increase in scrub typhus and other rickettsial infections in the last 5 years. As part of the public health response, the Mizoram Government has integrated screening (by rapid immunochromatographic test and/or Weil-Felix test) and line listing of scrub typhus and other rickettsial infections across all its health settings, a first in India. From 2018-22 (study period), 22914 cases were reported; of these, 19651 were positive for scrub typhus. Aizawl district is the worst affected, with 10580 cases (46.17%). The average incidence rate of rickettsial infections is 3.54 cases per 1000 persons-year, and the case fatality rate is 0.35. Patients with eschar (aOR=2.5, p<0.05), construction workers (aOR=17.9, p<0.05), and children aged 10 and below (aOR=5.4, p<0.05) have higher odds of death due to rickettsial infections.
Publisher
Cold Spring Harbor Laboratory
Reference44 articles.
1. Scrub Typhus [https://www.cdc.gov/typhus/scrub/index.html#:~:text=Scrub%20typhus%2C%20also%20known%20as,body%20aches%2C%20and%20sometimes%20rash.]
2. Clinical manifestations of scrub typhus
3. A Systematic Review of Mortality from Untreated Scrub Typhus (Orientia tsutsugamushi);PLoS neglected tropical diseases,2015
4. Scrub typhus;The Journal of the Association of Physicians of India,2005
5. Scrub typhus: a reemerging infection;Curr Opin Infect Dis,2020