Abstract
AbstractSummaryHigh throughput sequencing technologies have enabled cross-species comparative transcriptomic studies; however, there are numerous challenges for these studies due to biological and technical factors. We developed CoSIA (Cross-Species Investigation and Analysis), an Bioconductor R package and Shiny app that provides an alternative framework for cross-species transcriptomic comparison of non-diseased wild-type RNA sequencing gene expression data from Bgee across tissues and species (human, mouse, rat, zebrafish, fly, and nematode) through visualization of variability, diversity, and specificity metrics.Availability and Implementationhttps://github.com/lasseignelab/CoSIAContactBrittany Lasseigne (bnp0001@uab.edu)Supplementary informationSee Supplementary Files
Publisher
Cold Spring Harbor Laboratory