First detection and report of SARS-CoV-2 Spike protein N501Y mutations in Oklahoma USA

Author:

Narayanan Sai,Patil Girish,More Sunil,Saliki Jeremiah,Kaul Anil,Ramachandran Akhilesh

Abstract

AbstractWe describe the detection of SARS-CoV-2 (VOC)B.1.1.7 lineage in Oklahoma, USA. Various mutations in the S gene and ORF8 with similarity to the genome of B.1.1.7 lineage were detected in 4 of the 6 genomes sequenced and reported here. The sequences have been made available in GISAID. Presence of novel lineages indicate the need for frequent whole genome sequencing to better understand pathogen dynamics in different geographical locations.

Publisher

Cold Spring Harbor Laboratory

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