Diversity of coelomycetous fungi in human infections: a 10-year experience of two European reference centres

Author:

Garcia-Hermoso Dea,Valenzuela-Lopez Nicomedes,Rivero-Menendez Olga,Alastruey-Izquierdo AnaORCID,Guarro Josep,Cano-Lira José F.ORCID,Stchigel Alberto M.,

Abstract

ABSTRACTThe coelomycetous fungi are difficult to properly identify from their phenotypic characterization and their role as etiologic agents of human infections is not clear. We studied the species distribution of these fungi among clinical isolates that had been collected and stored over a ten-year period in two European reference laboratories (France and Spain). We identified phenotypically and molecularly 97 isolates by sequencing the D1-D2 fragment of the 28S nrRNA (LSU) gene. Species of the ordersPleosporalesandGlomerellaleswere present in both collections, andBotryosphaerialesandDiaporthalesonly in the French one. The most prevalent species wereMedicopsis romeroi,Neocucurbitaria keratinophila,Neocucurbitaria unguis-hominisandParaconiothyrium cyclothyrioides, which had been recovered primarily from superficial tissues. TheDidymellaceaewas the most common family represented, with 27 isolates distributed into five genera.

Publisher

Cold Spring Harbor Laboratory

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