FlowAtlas.jl: an interactive tool bridging FlowJo with computational tools in Julia

Author:

Coppard Valerie,Szep Grisha,Georgieva ZoyaORCID,Howlett Sarah K.,Jarvis Lorna B.ORCID,Rainbow Daniel B.ORCID,Suchanek OndrejORCID,Needham Edward J.ORCID,Mousa Hani S.ORCID,Menon David K.ORCID,Feyertag Felix,Mahbubani Krishna T.,Saeb-Parsy Kourosh,Jones Joanne L.ORCID

Abstract

AbstractAs the dimensionality, throughput, and complexity of cytometry data increases, so does the demand for user-friendly, interactive analysis tools that leverage high-performance machine learning frameworks. Here we introduce FlowAtlas.jl: an interactive web application that bridges the user-friendly environment of FlowJo and computational tools in Julia developed by the scientific machine learning community. We demonstrate the capabilities of FlowAtlas using a novel human multi-tissue, multi-donor immune cell dataset, highlighting key immunological findings.

Publisher

Cold Spring Harbor Laboratory

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