Benefits of timed mating over blind mating of mice to get timed embryos

Abstract

AbstractMus Musculushas provided scientists a well-adapted animal for the developmental studies. There is one on one co-relation between higher mammalian genes to mice genes hence making them superior model to study expression and translation research. Albino strain of house mice were used in this study with comparison of random or blind matings in mice and timed pregnant mice. The working behind blind matings is minimal and maintenance time and required force was also minimal as compared to timed matings. The results of comparisons of weight gain with pregnancies was similar in two groups where some un-pregnant mice also showed average or above average weight gain with time. The accurate embryonic stages requirement for the two experiments were e13.5, e14.5 and e15.5 (peak of neurogenesis in mice). The timed matings showed to be superior regarding total pregnancies and having accurate stages and is recommended to be used in order to save trouble of not getting what you require and more sacrifice of mice then is needed.