Author:
Archbold Georgina E.,Dobbek Nick,Nader Karim
Abstract
Evidence suggests that extinction is new learning. Memory acquisition involves both short-term memory (STM) and long-term memory (LTM) components; however, few studies have examined early phases of extinction retention. Retention of auditory fear extinction was examined at various time points. Shortly (1–4 h) after extinction acquisition spontaneous recovery was high compared to that after longer delays (8–24 h). Recall of a consolidated extinction trace was also impaired if it was preceded 1 h by extinction of a novel CS; propranolol did not attenuate this effect. These results suggest poor extinction retention reflects a retrieval impairment caused by the aversive experience of extinction training.
Publisher
Cold Spring Harbor Laboratory
Subject
Cellular and Molecular Neuroscience,Cognitive Neuroscience,Neuropsychology and Physiological Psychology
Cited by
7 articles.
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