The Clinical Effectiveness of One-Dose HPV Vaccine: A meta-analysis of 902,368 vaccinated women-Reference-Cited by-同舟云学术

The Clinical Effectiveness of One-Dose HPV Vaccine: A meta-analysis of 902,368 vaccinated women

Published:2023-08-23 Issue: Volume: Page:
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Author:

Setiawan Didik^ORCID,Nurulita Nunuk Aries,Khoirunnisa Sudewi Mukaromah,Postma Maarten J

Abstract

AbstractIntroductionAlthough the effectiveness of the HPV vaccine has been comprehensively described, adherence to dosing and limited budget is one of the causes of delay in HPV vaccination implementation in a country. A one-dose HPV vaccine could possibly solve those issues since several studies show promising results.Areas coveredThis is a systematic review and meta-analysis focusing on the effectiveness of the one-dose HPV vaccine compared to two- and three doses of vaccination. We focused on clinical effectiveness, including prevention of HPV16, HPV18, and hrHPV infection, HSIL or ASC-H incidence, and CIN II/III incidence.Expert opinionOur review showed that a one-dose HPV vaccine could potentially be as effective as two-or three doses since it offers immunogenic protection up to 8 years follow up and also prevention on infection and pre-cancers incidence. However, more studies and an extended duration of existing studies are required in order to provide robust evidence of this recommendation.

Publisher

Cold Spring Harbor Laboratory

Reference43 articles.

1. Ferlay J , Soerjomataram I , Ervik M , Dikshit R , Eser S , Mathers C , Rebelo M , Parkin DM , Forman D , Bray F. GLOBOCAN 2012 v1.0, Cancer Incidence and Mortality Worldwide: IARC CancerBase No. 11 [Internet]. Lyon, France: International Agency for Research on Cancer. 2013 [cited 2014 Aug 17]. Available from: http://globocan.iarc.fr

2. Viral load in the natural history of human papillomavirus type 16 infection: A nested case-control study;J Infect Dis [Internet],2011

3. Lacau Saint Guily J, Moyal-Barracco M, Jacquard A, Largeron N, Dahlab A;Epidemiology, treatment pathways and costs of cancers potentially related to HPV infection in France. Value Heal [Internet],2016

4. EAU guidelines on the treatment and follow-up of non-neurogenic male lower urinary tract symptoms including benign prostatic obstruction;Eur Urol [Internet],2013

5. Immunogenicity and tolerability of an HPV-16/18 AS04-adjuvanted prophylactic cervical cancer vaccine in women aged 15–55 years