The WORC database: MRI and CT scans, segmentations, and clinical labels for 930 patients from six radiomics studies

Author:

Starmans Martijn P.A.ORCID,Timbergen Milea J.M.ORCID,Vos MelissaORCID,Padmos Guillaume A.,Grünhagen Dirk J.ORCID,Verhoef CornelisORCID,Sleijfer Stefan,van Leenders Geert J.L.H.ORCID,Buisman Florian E.ORCID,Willemssen Francois E.J.A.,Koerkamp Bas GrootORCID,Angus LindsayORCID,van der Veldt Astrid A.M.,Rajicic Ana,Odink Arlette E.,Renckens Michel,Doukas Michail,de Man Rob A.,IJzermans Jan N.M.ORCID,Miclea Razvan L.,Vermeulen Peter B.,Thomeer Maarten G.,Visser Jacob J.ORCID,Niessen Wiro J.ORCID,Klein StefanORCID

Abstract

AbstractThe WORC database consists in total of 930 patients composed of six datasets gathered at the Erasmus MC, consisting of patients with: 1) well-differentiated liposarcoma or lipoma (115 patients); 2) desmoid-type fibromatosis or extremity soft-tissue sarcomas (203 patients); 3) primary solid liver tumors, either malignant (hepatocellular carcinoma or intrahepatic cholangiocarcinoma) or benign (hepatocellular adenoma or focal nodular hyperplasia) (186 patients); 4) gastrointestinal stromal tumors (GISTs) and intra-abdominal gastrointestinal tumors radiologically resembling GISTs (246 patients); 5) colorectal liver metastases (77 patients); and 6) lung metastases of metastatic melanoma (103 patients). For each patient, either a magnetic resonance imaging (MRI) or computed tomography (CT) scan, collected from routine clinical care, one or multiple (semi-)automatic lesion segmentations, and ground truth labels from a gold standard (e.g., pathologically proven) are available. All datasets are multicenter imaging datasets, as patients referred to our institute often received imaging at their referring hospital. The dataset can be used to validate or develop radiomics methods, i.e., using machine or deep learning to relate the visual appearance to the ground truth labels, and automatic segmentation methods. See also the research article related to this dataset: Starmans et al., Reproducible radiomics through automated machine learning validated on twelve clinical applications, Submitted.Specifications Table

Publisher

Cold Spring Harbor Laboratory

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