Author:
Cohen Eli J.,Quek Rui Tong,Beeby Morgan
Abstract
AbstractCampylobacter jejuniis responsible for tens of millions of cases of gastroenteritis each year. Despite its prevalence and impact on human health, the repertoire of genetic tools available for researchers to studyC. jejuniremains limited. In order to expand upon the genetic toolkit in this species, we have engineered a system for generating conditional knockouts based on thetetRAtetracycline-resistance cassette. This system exhibits tight repressibility and titratability of target-gene expression and will be useful for future research on this important human pathogen.
Publisher
Cold Spring Harbor Laboratory
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