Methods for High Fidelity Spectral Data Collection for Generating Ground Truth Data for Simulated Tissues
Author:
Gong Alex T.,Dulal Arjun,Crane Matthew M.,Reihsen Troy E.,Sweet Robert M.,Mendenhall Alexander R.
Abstract
ABSTRACTOur research is focused on creating and simulating hyper-realistic artificial human tissue analogues. Generation and simulation of macroscopic biological material depends upon accurate ground-truth data on spectral properties of materials. Here, we developed methods for high fidelity spectral data collection using two differently colored simulated skin tissue samples and a portable spectral imaging camera. Using the standard procedure, we developed, we quantified the reproducibility of the spectral image signatures of the two synthetic skin samples under natural and artificial lighting conditions commonly found in clinical settings. We found high coefficients of determination for all measures taken under the same lighting. As expected, we found the spectral image signature of each sample was dependent on the illumination source. Our results confirm that illumination spectra data should be included with spectral image data. The high-fidelity methods for spectral image data collection we developed here should facilitate accurate collection of spectral image signature data for gross biological samples and synthetic materials collected under the same illumination source.
Publisher
Cold Spring Harbor Laboratory
Reference61 articles.
1. Donaldson, M. S. , Corrigan, J. M. & Kohn, L. T. To err is human: building a safer health system. 6, (National Academies Press, 2000).
2. Medical error—the third leading cause of death in the US
3. Application of the “See One, Do One, Teach One” Concept in Surgical Training
4. Beyond “see one, do one, teach one”: toward a different training paradigm;Qual. Saf. Heal. Care,2009
5. The Use of Human Patient Simulators