Babesia microti with multiple resistance mutations detected in an immunocompromised patient receiving atovaquone prophylaxis

Abstract

AbstractWe reportBabesia microtigenomic sequences with multiple mutations in the atovaquone-target region of cytochrome b and the azithromycin-associated ribosomal protein L4, including newly identified mutations. The parasite was sequenced from an immunocompromised patient on prophylactic atovaquone forPneumocystispneumonia for several weeks before the diagnosis of babesiosis.