Clock time: a foreign measure to brain dynamics

Abstract

AbstractHuman thought is highly flexible and dynamic, achieved by evolving patterns of brain activity across groups of cells. Neuroscience aims to understand cognition in the brain by analysing these intricate patterns. Here, we argue that this goal is impeded by the time format of our data – clock time. The brain is a system with its own dynamics and regime of time, with no intrinsic concern for the human-invented second. A more appropriate time format is cycles of brain oscillations, which coordinate neural firing and are widely implicated in cognition. These brain dynamics do not obey clock time – they start out of tune with clock time and drift apart even further as oscillations unpredictably slow down, speed up, and undergo abrupt changes. Since oscillations clock cognition, their dynamics should critically inform our analysis. We describe brain time warping as a new method to transform data in accordance with brain dynamics, which sets the time axis to cycles of clocking oscillations (a native unit) rather than milliseconds (a foreign unit). We also introduce the Brain Time Toolbox, a software library that implements brain time warping for electrophysiology data and tests whether it reveals information patterns in line with how the brain uses them.