Abstract
AbstractAn estimated 2.4 million newborn infants died in 2020, 80% of them in sub-Saharan Africa and South Asia. To achieve the Sustainable Development Target for neonatal mortality reduction, countries with high mortality need to implement evidence-based, cost-effective interventions at scale. Our study aimed to estimate the cost, cost-effectiveness, and benefit-cost ratio of a participatory women’s groups intervention scaled up by the public health system in Jharkhand, eastern India. The intervention was evaluated through a pragmatic cluster non-randomised controlled trial in six districts. We estimated the cost of the intervention from a provider perspective, with a 42-month time horizon for 20 districts. We estimated costs using a combination of top-down and bottom-up approaches. All costs were adjusted for inflation, discounted at 3% per year, and converted to 2020 International Dollars (INT$). Incremental cost-effectiveness ratios (ICERs) were estimated using extrapolated effect sizes for the impact of the intervention in 20 districts, in terms of cost per neonatal deaths averted and cost per life year saved. We assessed the impact of uncertainty on results through one-way and probabilistic sensitivity analyses. We also estimated benefit-cost ratio using a benefit transfer approach. Total intervention costs for 20 districts were INT$ 15,017,396. The intervention covered an estimated 1.6 million livebirths across 20 districts, translating to INT$ 9.4 per livebirth covered. ICERs were estimated at INT$ 1,272 per neonatal death averted or INT$ 41 per life year saved. Net benefit estimates ranged from INT$ 1,046 million to INT$ 3,254 million, and benefit-cost ratios from 71 to 218. Our study suggests that participatory women’s groups scaled up by the public health system are highly cost-effective in improving neonatal survival and have a very favourable return on investment. The intervention can be scaled up in similar settings within India and other countries.
Publisher
Cold Spring Harbor Laboratory
Reference38 articles.
1. UNICEF. Levels & Trends in Child Mortality: Report 2020 2020 [cited 2021 15 December]. Available from: https://data.unicef.org/resources/levels-and-trends-in-child-mortality-2020/.
2. How many lives are at stake? Assessing 2030 sustainable development goal trajectories for maternal and child health
3. Can available interventions end preventable deaths in mothers, newborn babies, and stillbirths, and at what cost?;The Lancet,2014
4. Hug L , Sharrow D , Zhong K , You D , on behalf of the United Nations Inter-agency Group for Child Mortality Estimation. Levels and Trends in Child Mortality: Report 2018. New York: United Nations Children’s Fund, 2018.
5. World Health Organization. Global Strategy for Women’s, Children’s and Adolescents’ Health (2016-2030): World Health Organization; 2010 [cited 2021 15 December]. Available from: https://www.who.int/data/maternal-newborn-child-adolescent-ageing/global-strategy-data.