Abstract
AbstractLeft displacement of the abomasum (LDA) is a common condition in Holstein population mainly occur around the time of parturition. The entrapped abomasum located between the rumen and the abdominal wall caused by the abomasal hypomotility. The heritability of LDA estimated higher than for other bovine diseases but a number of management and nutritional conditions are also affecting the disease appearance. Genome studies revealed many significant genomic regions associated with LDA, although an RNA sequencing analysis of abomasum is missing from the literature. Within the framework of this research, we tried to patch up this area missing from the literature and to reveal the genetic causes and a complex interaction between the endocrine and neuromuscular pathways behind the symptoms of the disease with the help of transcriptomic analysis.
Publisher
Cold Spring Harbor Laboratory
Reference31 articles.
1. Effect of duodenal alkalinization on gastric motility;Gastroenterology,1966
2. The Further Purification of Motilin, a Gastric Motor Activity Stimulating Polypeptide from the Mucosa of the Small Intestine of Hogs
3. Chu, C. P. , Hokamp, J. A. , Cianciolo, R. E. , Dabney, A. R. , Brinkmeyer-Langford, C. , Lees, G. E. , & Nabity, M. B. (2017). RNA-seq of serial kidney biopsies obtained during
4. Immunochemical characterisation of somatostatin in ruminants;Regulatory peptides,1988