Author:
Lüke Florian,Haller Florian,Utpatel Kirsten,Krebs Markus,Meidenbauer Norbert,Scheiter Alexander,Spörl Silvia,Heudobler Daniel,Keil Felix,Schubart Christoph,Tögel Lars,Einhell Sabine,Dietmaier Wolfgang,Huss Ralf,Dintner Sebastian,Sommer Sebastian,Jordan Frank,Goebeler Maria-Elisabeth,Metz Michaela,Haake Diana,Scheytt Mithun,Gerhard-Hartmann Elena,Maurus Katja,Brändlein Stephanie,Rosenwald Andreas,Hartmann Arndt,Märkl Bruno,Einsele Hermann,Mackensen Andreas,Herr Wolfgang,Kunzmann Volker,Bargou Ralf,Beckmann Matthias W.,Pukrop Tobias,Trepel Martin,Evert Matthias,Claus Rainer,Kerscher Alexander
Abstract
ABSTRACTBackgroundMolecular Tumor Boards (MTBs) are crucial instruments for discussing and allocating targeted therapies to suitable cancer patients based on genetic findings. Currently, limited evidence is available regarding the regional impact and the outreach component of MTBs.MethodsWe analyzed MTB patient data from four neighboring Bavarian tertiary care oncology centers in Würzburg, Erlangen, Regensburg, and Augsburg, together constituting the WERA Alliance. Absolute patient numbers and regional distribution across the WERA-wide catchment area were weighted with local population densities.ResultsHighest MTB patient numbers were found close to the four cancer centers. However, peaks in absolute patient numbers were also detected in more distant and rural areas. Moreover, weighting absolute numbers with local population density allowed us to identify regions within our catchment area relatively underrepresented in WERA MTBs.ConclusionInvestigating patient data from four neighboring cancer centers, we comprehensively assessed the regional impact of our MTBs. The results confirmed the success of existing collaborative structures with our regional partners. Additionally, our results help identifying potential white spots in precision oncology and establishing a joint WERA-wide outreach strategy.
Publisher
Cold Spring Harbor Laboratory