Abstract
AbstractMedicinal properties of Euphorbia tirucalli L. have been investigated in vitro. Water extract from the plant latex was freeze dried and tested against 3 digestive enzymes and showed IC50 as 39.8±0.22, 79.43±0.38 and 316.22±0.3 for lipase, alpha- glucosidase and alpha- amylase, respectively. These results were incomparable with drugs such as acarbose and orlistat. Antioxidant property showed that the IC50 values of E. tirucalli and Trolox were 79.43±0.69 and 3.1 ±0.92 respectively. Also, the plant extract exhibited a range of antimicrobial activity against gram-positive and gram-negative bacteria and pathogenic yeast and fungi. Cytotoxicity of the plant extract tested on Caco-2 cells was determined using MTT method. The effect was linear and almost 0.5 mg/ml extract has inhibited 50% of cells relative to the control. Euphorbia tirucalli showed promising activities and is potential source of active ingredient with functional properties.
Publisher
Cold Spring Harbor Laboratory
Reference36 articles.
1. Comparison of anticancer effect of Pleurotus ostreatus extract with doxorubicin hydrochloride alone and plus thermotherapy on erythroleukemia cell line
2. Khalil A. Role of Biotechnology in Alkaloids Production. Catharanthus roseus. Germany: Springer; 2017; 59–70.
3. Cardiovascular and metabolic consequences of obesity;Frontiers in physiology,2015
4. Tazelaar HD , Lilenbaum RC. Pathology of lung malignancies. Up To Date, Nicholson A , Jett J , Lilenbaum R [Section Editors], Up To Date, Vora S[consultado 18 Mar 2017] Disponible en: https://uptodate_publicaciones_saludcastillayleones/contents/pathology-of-lung-malignancies.1-19.
5. Prevalence of Obesity, Diabetes, and Obesity-Related Health Risk Factors, 2001
Cited by
2 articles.
订阅此论文施引文献
订阅此论文施引文献,注册后可以免费订阅5篇论文的施引文献,订阅后可以查看论文全部施引文献