Virological traits of the SARS-CoV-2 BA.2.87.1 lineage-Reference-Cited by-同舟云学术

Virological traits of the SARS-CoV-2 BA.2.87.1 lineage

Published:2024-02-28 Issue: Volume: Page:
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Author:

Zhang Lu,Dopfer-Jablonka Alexandra,Nehlmeier Inga,Kempf Amy,Graichen Luise,Hampel Noemí Calderón,Cossmann Anne,Stankov Metodi V.,Ramos Gema Morillas,Schulz Sebastian R.,Jäck Hans-Martin^ORCID,Behrens Georg M. N.,Pöhlmann Stefan^ORCID,Hoffmann Markus^ORCID

Abstract

AbstractThe highly mutated SARS-CoV-2 BA.2.87.1 lineage was recently detected in South Africa, but its transmissibility is unknown. Here, we report that BA.2.87.1 efficiently enters human cells but is more sensitive to antibody-mediated neutralization than the currently dominating JN.1 variant. Acquisition of adaptive mutations might thus be needed for high transmissibility.

Publisher

Cold Spring Harbor Laboratory

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1. Antigenicity assessment of SARS-CoV-2 saltation variant BA.2.87.1;Emerging Microbes & Infections;2024-05-02

2. SARS-CoV-2 Omicron BA.2.87.1 Exhibits Higher Susceptibility to Serum Neutralization Than EG.5.1 and JN.1;2024-03-11

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