Cross-species real time detection of trends in pupil size fluctuation

Author:

Kronemer Sharif I.ORCID,Gobo Victoria E.,Walsh Catherine R.,Teves Joshua B.,Burk Diana C.ORCID,Shahsavarani Somayeh,Gonzalez-Castillo JavierORCID,Bandettini Peter A.

Abstract

AbstractPupillometry is a popular method because pupil size is easily measured, sensitive to central neural activity, and associated with behavior, cognition, emotion, and perception. Currently, there is no method for online monitoring phases of pupil size fluctuation. We introducertPupilPhase– an open source software that automatically detects trends in pupil size in real time, enabling novel implementations of real time pupillometry towards achieving numerous research and translational goals. We validated the performance of rtPupilPhase on human, rodent, and monkey pupil data and propose future applications of real time pupillometry.

Publisher

Cold Spring Harbor Laboratory

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