Abstract
The fibrotic lesion formation is the main deterrent at regeneration of neurons in CNS injuries. In this paper we studied fibrotic scar formation in rat corticospinal tract lesion after one year survival time. The glial scar formation and Extracellular Matrix (ECM) fibronection derived scaffolds were investigated and the fore paw reaching task was performed during this period to see whether there is any regeneration of neurons along the lesion or not.
Publisher
Cold Spring Harbor Laboratory